Doctoral candidate

Kassandra Chérubin

DC4

University of Nottingham, United Kingdom

“What excites me the most about HEAL4WARD is the opportunity to contribute to healthcare research through a multidisciplinary approach, while meeting people from different backgrounds who share my passion for biomaterials. By learning new techniques, developing my knowledge and working in different research environments, I hope to improve my adaptability and gain confidence in my abilities as a researcher.”

Biography

About Kassandra Chérubin

Kassandra Chérubin completed her studies at Sorbonne Université, France, where she obtained a Bachelor’s degree in Chemistry and a Master’s degree in Materials Chemistry, specialising in Formulation and Polymers. During her studies, she explored nanomaterials for healthcare applications, particularly in cancer treatment, and investigated the biomedical applications of polymers and biomaterials through literature reviews.
As part of her Master’s degree, she completed two research internships: a five-month internship at Okayama University in Japan, where she worked on recovering valuable elements from industrial waste through acid treatment, and a six-month industrial internship at Saint-Gobain Research Paris, focusing on the formulation of coloured sol-gel coatings for glass. These experiences allowed her to investigate how experimental parameters influence material properties, develop a structured approach to experimental design and formulation, and strengthen her research skills and adaptability in different research environments.
Her research interests focus on formulation and biomaterials for healthcare applications. While she valued the practical research experience gained during both internships, her coursework and literature reviews on biomaterials and biomedical applications particularly strengthened her interest in the healthcare sector, motivating her to pursue further research in this field.

Doctoral project

3D-printing of microneedle patches from synthetic swellable and fast degrading polymers for on-demand wound healing

This PhD project focuses on developing synthetic, swellable and fast-degrading polymers for the fabrication of microneedle patches using advanced 3D-printing technologies. It involves the synthesis of novel polymeric materials, their formulation into printable inks and the optimisation of additive manufacturing processes to produce high-resolution, multi-material devices incorporating antimicrobial and theragnostic nanomaterials developed within the HEAL4WARD network.
The project aims to establish a versatile and customisable platform for microneedle fabrication that enables controlled drug delivery and adaptation to different wound types, supporting more personalised wound care while ensuring biocompatibility and sustainability. It also aims to develop polymeric materials based on renewable and degradable resources, using largely natural enzymatic catalysts for their fabrication.
The expected results include polymeric nano-delivery devices offering optimal drug encapsulation and high therapeutic efficacy. These new polymeric platforms will also contribute to the development of novel and sustainable materials for next-generation 3D-printing technologies, drug delivery systems and biofabrication.
Since Kassandra wants to pursue a career in biomaterials research for healthcare applications, with a particular interest in drug delivery systems, this project closely aligns with her scientific interests and career aspirations. In addition, the international mobility aspect makes this PhD particularly attractive to her, as she greatly enjoys working in international environments and developing her adaptability. She therefore sees this project as an excellent opportunity to deepen her scientific knowledge, acquire new skills and gain valuable international research experience.

Research interests

Biomaterials

Formulation

Polymers

Healthcare

At a glance

Host institution

University of Nottingham

Country

United Kingdom

Main supervisor

Dr Vincenzo Taresco

Secondments

Secondment 1

CNRS-ICMPE, France

Purpose: To investigate nanoparticles modification for compatibility with the printable resin formulations developed in this project, and thus identify the most suitable 3D printing technology.

Secondment 2

University of Vigo, Spain

Purpose: To evaluate the performance of 3D-printed microneedles developed in this project, using a biofilm model from University of Vigo, focusing on penetration, degradability and overall functionality.