Supervisor

Gustavo Bodelón González

Professor at the Department of Functional Biology and Health Sciences

University of Vigo

“HEAL4WARD offers a unique opportunity to translate advances in microbiology, nanotechnology, and SERS into new tools for the rapid and accurate detection of wound infections. I am excited to contribute our expertise in surface-enhanced Raman scattering (SERS)-based biosensing and work across disciplines to develop innovative diagnostic strategies with real potential to improve the management of chronic wound infections.”

Background

Scientific background

Gustavo Bodelón González began his scientific career with an MSc in Microbiology at the University of Oklahoma in the USA, followed by a PhD in Biochemistry and Molecular Biology at the University of Santiago de Compostela in Spain. His postdoctoral research at the Ludwig Institute for Cancer Research in London focused on the molecular mechanisms underlying Epstein-Barr virus-induced tumorigenesis. He then spent several years at the Spanish National Centre for Biotechnology (CNB-CSIC), where he worked on bacterial secretion systems.In 2012, Gustavo joined the University of Vigo, where his research progressively evolved towards the interface of microbiology and nanotechnology, with a particular focus on the use of SERS to study and detect microbial processes. He currently leads a research line within the Functional NanoBioMaterials group at CINBIO-University of Vigo, developing SERS-based approaches for microbial biosensing, molecular imaging, diagnostics and biomedical applications.His research has been supported by competitive national and European funding and has resulted in 34 publications, with an h-index of 26.

Personal background

Gustavo Bodelón González is from Vigo, in northwestern Spain, and has always been fascinated by biological processes at the molecular and cellular levels. His scientific path began in molecular microbiology and virology and later expanded to bacterial engineering and host-microbe interactions. A turning point in Gustavo’s career was working at the interface with materials science and nanotechnology, which led him to explore plasmonic nanomaterials and SERS as powerful tools for studying microbial processes and addressing biomedical challenges such as the detection and treatment of bacterial infections.Alongside his research, he teaches Microbiology at the University of Vigo and is actively involved in the training and mentoring of early-career researchers. Gustavo has supervised three completed PhD theses, as well as numerous Master’s and Bachelor’s students and research trainees. Research, teaching and mentoring are complementary aspects of his academic role, and he particularly values the opportunity to bring them together within the HEAL-4WARD Marie Skłodowska-Curie Doctoral Network.


key publications

 

  • De Marchi, S., Bodelón, G., Vázquez-Iglesias, L., Liz-Marzán, L.M., Pérez-Juste, J., Pastoriza-Santos, I. (2019) Surface-enhanced Raman scattering (SERS) imaging of bioactive metabolites in mixed bacterial populations. Applied Materials Today 14, 207–215. https://doi.org/10.1016/j.apmt.2018.12.005

 

  • Bodelón, G., Montes-García, V., Pérez-Juste, J., Pastoriza-Santos, I. (2018) Surface-Enhanced Raman Scattering Spectroscopy for Label-Free Analysis of aeruginosa Quorum Sensing. Frontiers in Cellular and Infection Microbiology 8, 143. https://doi.org/10.3389/fcimb.2018.00143

 

  • Bodelón, G., Montes-García, V., López-Puente, V., Costas, C., Pérez-Juste, I., Pérez-Juste, J., Pastoriza-Santos, I., Liz-Marzán, L.M. (2017) Imaging bacterial interspecies chemical interactions by surface-enhanced Raman scattering. ACS Nano 11, 4631–4640. https://doi.org/10.1021/acsnano.7b00258

 

  • Bodelón, G., Montes-García, V., López-Puente, V., Hill, E.H., Hamon, C., Sanz-Ortiz, M.N., Rodal-Cedeira, S., Costas, C., Celiksoy, S., Pérez-Juste, I., Scarabelli, L., La Porta, A., Pérez-Juste, J., Pastoriza-Santos, I., Liz-Marzán, L.M. (2016) Detection and imaging of quorum sensing in Pseudomonas aeruginosa biofilm communities by surface-enhanced resonance Raman scattering. Nature Materials 15, 1203–1211. https://doi.org/10.1038/nmat4720

Project Involvement and Roles

Within HEAL-4WARD, Gustavo Bodelón González is Principal Investigator of two complementary doctoral projects, DC3 and DC10, focused on developing SERS-active 3D models to investigate chronic wound infections. DC3 examines how the mechanical and biochemical properties of the wound microenvironment influence mono- and multispecies biofilm development, while DC10 focuses on bioengineered plasmonic 3D human skin models for non-invasive monitoring of bacterial infection and responses to antimicrobial treatments.

Together, these projects combine microbiology, plasmonic nanomaterials and label-free SERS to better understand biofilm behaviour and develop new strategies for monitoring and managing chronic wound infections. Gustavo will also host and supervise secondments of several HEAL-4WARD doctoral candidates at the University of Vigo, providing training and access to his group’s expertise in microbiology, SERS-based detection and microbial molecular imaging.

Current activities

Gustavo Bodelón González is currently Associate Professor of Microbiology at the University of Vigo and Principal Investigator of the Functional NanoBioMaterials group (FunNanoBIO) at CINBIO. His research lies at the interface of microbiology, molecular biology, nanotechnology and SERS, with a particular focus on developing new strategies for microbial biosensing and molecular imaging.

A major goal of Gustavo’s group is to exploit plasmonic nanomaterials and naturally produced bacterial metabolites as molecular reporters to monitor microbial processes non-invasively and in real time.