Supervisor
Professor of Internal Medicine and Infectious Diseases; Supervisor of the Immunology of Infectious Diseases Laboratory and Out-Patient Centre, ATTIKON University Hospital; Director of the MSc in Infectious Diseases
National and Kapodistrian University of Athens, Medical School
Background
Evangelos J. Giamarellos-Bourboulis graduated from the Medical School of the National and Kapodistrian University of Athens in 1994 and completed his PhD in 1998 on the antimicrobial activity of polyunsaturated fatty acids against Gram-negative bacteria. After specialist training in Internal Medicine, he undertook advanced training in the immunology of infectious diseases at Radboud University Nijmegen in the Netherlands. He joined the academic staff of the University of Athens in 2001 and became Professor of Internal Medicine and Infectious Diseases in 2018.His scientific work has centred on the heterogeneity of host immune responses in sepsis and on biomarker-guided therapeutic strategies. Evangelos has led major investigator-initiated studies, including SAVE, SAVE-MORE and ImmunoSep, and has contributed to international research on privacy-preserving clinical machine learning.He is also President of the Hellenic Institute for the Study of Sepsis, Chair of the European Sepsis Alliance, a Board Member of the Global Sepsis Alliance and President of the Hellenic Society for Chemotherapy. He currently has 48,200 citations, an h-index of 100 and an i10-index of 450.
Evangelos J. Giamarellos-Bourboulis was born in Athens, Greece, where he has spent most of his life. Early in his medical career, he became interested in why patients with apparently similar infections can follow very different clinical courses. This question led him to investigate the interaction between pathogens and the host immune response and, ultimately, to pursue precision approaches that match diagnosis and treatment to each patient’s biological profile.He chose an academic clinical path because it allows him to combine patient care, experimental research, collaborative clinical trials and the mentoring of young scientists.
key publications
As Principal Investigator for the National and Kapodistrian University of Athens, Evangelos J. Giamarellos-Bourboulis is the primary supervisor of DC11, “AI for early recognition, diagnosis and personalised treatment strategies for sepsis”. He will guide the clinical definition of the research questions, the selection and interpretation of clinical and biological predictors, the validation of AI outputs, and the translation of findings into clinically meaningful decision-support approaches.
Evangelos will also host and mentor the UoA secondment of DC8 on sepsis-proofing wound care and the clinical implications of multispecies biofilms. Across the HEAL-4WARD network, he will contribute training in sepsis pathophysiology, precision medicine, biomarker-guided treatment, clinical-trial methodology, research ethics and the responsible use of health data and AI.
Evangelos J. Giamarellos-Bourboulis is Professor of Internal Medicine and Infectious Diseases at the Medical School of the National and Kapodistrian University of Athens. At ATTIKON University Hospital, he supervises the Immunology of Infectious Diseases Laboratory and Out-Patient Centre and directs the MSc programme in Infectious Diseases.
His group combines clinical investigation, immunology, biomarker research and data-driven analysis to understand severe infections and translate mechanistic findings into diagnostic and therapeutic strategies.
Evangelos’s research focuses particularly on sepsis endotypes, immunoparalysis, macrophage activation, precision immunotherapy, antimicrobial resistance and the immunobiology of hidradenitis suppurativa. He also designs and coordinates investigator-initiated and multicentre clinical studies, supervises doctoral and postgraduate researchers, and leads collaborative activities through the Hellenic Institute for the Study of Sepsis and international sepsis networks.
